Table 2.
Baseline characteristics of study population according to hyperuricemia or not by gender.
| Variables | Female | Male | ||||
|---|---|---|---|---|---|---|
| Non-Hyperuricemia | Hyperuricemia | p-value | Non-Hyperuricemia | Hyperuricemia | p-value | |
| Age (year) | 53.1 ± 10.2 | 57.8 ± 10.6 | <0.001 | 54.6 ± 10.8 | 53.2 ± 11.1 | 0.002 |
| SBP (mmHg) | 139.7 ± 2.8 | 146.4 ± 25.0 | <0.001 | 143.2 ± 22.6 | 145.6 ± 22.9 | 0.010 |
| DBP(mmHg) | 80.3 ± 11.4 | 83.9 ± 12.7 | <0.001 | 83.1 ± 11.6 | 87.2 ± 12.7 | <0.001 |
| Serum creatinine (mmol/L) | 64.3 ± 11.8 | 82.7 ± 63.1 | <0.001 | 78.1 ± 16.2 | 88.7 ± 30.3 | <0.001 |
| eGFR(mL/min) | 95.2 ± 14.3 | 88.0 ± 19.4 | <0.001 | 92.9 ± 15.4 | 75.6 ± 19.1 | <0.001 |
| Serum uric acid (μmol/L) | 245.1 ± 53.7 | 413.8 ± 54.7 | <0.001 | 309.9 ± 58.3 | 482.9 ± 62.6 | <0.001 |
| FPG (mmol/L) | 5.8 ± 1.6 | 6.2 ± 1.6 | <0.001 | 5.9 ± 1.7 | 6.0 ± 1.5 | 0.705 |
| TC (mmol/L) | 5.3 ± 1.1 | 5.8 ± 1.3 | <0.001 | 5.1 ± 1.0 | 5.5 ± 1.2 | <0.001 |
| TG (mmol/L) | 1.6 ± 1.2 | 2.5 ± 2.2 | <0.001 | 1.5 ± 1.4 | 2.5 ± 2.7 | <0.001 |
| HDL-C (mmol/L) | 1.4 ± 0.3 | 1.3 ± 0.3 | <0.001 | 1.4 ± 0.4 | 1.3 ± 0.4 | <0.001 |
| LDL-C (mmol/L) | 2.9 ± 0.8 | 3.3 ± 0.9 | <0.001 | 2.8 ± 0.8 | 3.0 ± 0.8 | <0.001 |
| Dietscore | 2.1 ± 1.1 | 2.0 ± 1.1 | 0.009 | 2.5 ± 1.1 | 2.6 ± 1.1 | 0.101 |
| BMI(kg/m2) | 24.7 ± 3.7 | 26.7 ± 3.8 | <0.001 | 24.5 ± 3.4 | 26.4 ± 3.9 | <0.001 |
| Race group (han) | 5361 (94.8%) | 374 (97.4%) | 0.010 | 4092 (94.7%) | 646 (95.6%) | 0.200 |
| Education | <0.001 | 0.535 | ||||
| Primary school or below | 3173 (56.1%) | 258 (67.2%) | 1811 (41.9%) | 278 (41.1%) | ||
| Middle school | 2047 (36.2%) | 97 (25.3%) | 2036 (47.1%) | 314 (46.4%) | ||
| High school or above | 438 (7.7%) | 29 (7.6%) | 474 (11.0%) | 84 (12.4%) | ||
| Physical activity | 0.010 | 0.001 | ||||
| Low | 3173 (56.1%) | 374 (97.4%) | 913 (21.1%) | 180 (26.6%) | ||
| Moderate | 2047 (36.2%) | 10 (2.6%) | 3160 (73.1%) | 471 (69.7%) | ||
| High | 438 (7.7%) | 384 (100.0%) | 248 (5.7%) | 25 (3.7%) | ||
| Currently smoking | 929 (16.4%) | 66 (17.2%) | 0.694 | 2504 (57.9%) | 351 (51.9%) | 0.002 |
| Family income (CNY/year) | 0.360 | 0.482 | ||||
| ≤5000 | 646 (11.4%) | 53 (13.8%) | 582 (13.5%) | 90 (13.3%) | ||
| 5000–20,000 | 3135 (55.4%) | 209 (54.4%) | 2349 (54.4%) | 353 (52.2%) | ||
| >20,000 | 1877 (33.2%) | 122 (31.8%) | 1390 (32.2%) | 233 (34.5%) | ||
| Medication used a | 0.004 | <0.001 | ||||
| Yes | 2277 (87.8%) | 317 (12.2%) | 2418 (96.6%) | 85 (3.4%) | ||
| No | 2008 (85.0%) | 355 (15.0%) | 3196 (91.5%) | 295 (8.5%) | ||
| Menopause status | <0.001 | |||||
| Yes | – | – | 3233 (91.9%) | 285 (8.1%) | ||
| No | – | – | 2385 (96.2%) | 94 (3.8%) | ||
Data are expressed as the mean ± SD or as n (%); QTc: corrected QT; CNY: China Yuan (1 CNY = 0.157 USD); BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; a Indicating any self-reported medication used in the past two weeks; ps: p for category from chi-square; for continous from non-parametric test.