Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jul 27;7:95. doi: 10.1186/s13287-016-0360-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — Inhibitory effect of ES-CM on tumor growth in vivo. a Firefly luciferase (Fluc) imaging of tumor progression. Representative animals injected with 2 × 10⁵ 4T1 (Fluc/GFP-pStat3/Rluc) cells after treatment with 4T1-CM and ES-CM for 48 h into the left and right of the fourth pair of mammary fat pads respectively. b Quantitative analysis of Fluc signal. **P < 0.01 vs 4T1-CM, n = 5. c, d Representative immunofluorescence staining of E-cadherin and CD31 of tumor tissue demonstrated a resistance of EMT progress and decreased tumor angiogenesis ability. Percentages of E-cadherin and CD31-positive cells are shown. Scale bar represents 100 μm. **P < 0.01 vs 4T1-CM, n = 3. See also Additional file 1: Figure S4. CM conditioned medium, ES embryonic stem, GFP green fluorescent protein