Table 10.
Prognostic factors for overall survival in CRC stage IV
| Overall survival | ||||||
|---|---|---|---|---|---|---|
| Variable | Univariate analysis | Multivariate analysis | ||||
| HR | 95 % CI | p | HR | 95 % CI | p | |
| Age (<45 years) | 2.116 | 0.938 – 4.774 | 0.071 | 0.898 | 0.271 - 2979 | 0.860 |
| Localization (rectum) | 0.684 | 0.350 – 1.447 | 0.267 | |||
| CEA (>5 ng/mL) | 2.017 | 1.117 – 3.641 | 0.020 | 1.834 | 0.946 – 3.553 | 0.072 |
| Differentiation (Poorly/undifferentiated) | 2.748 | 1.470 – 5.138 | 0.002 | 3.488 | 1.563 – 7.782 | 0.002 |
| Spread lymph node (present) | 1.156 | 0.638 – 2.093 | 0.633 | |||
| Vessel invasion (present) | 1.312 | 0.733 – 2.351 | 0.361 | |||
| MCT1 (+) | 0.394 | 0.186 – 0.834 | 0.015 | 0.694 | 0.310 – 1.597 | 0.390 |
| MCT4 (+) | 1.429 | 0.767 – 2.664 | 0.261 | |||
| CD147 (+) | 0.779 | 0.412 – 1.473 | 0.442 | |||
| GLUT1 (+) | 1.169 | 0.642 – 2.129 | 0.610 | |||