. 2016 Jul 26;16:535. doi: 10.1186/s12885-016-2566-9

Table 6.

Assessment of associations between proteins plasma membrane expression in CRC lymph node metastasis and clinical data

	MCT1			MCT4			CD147			GLUT1
	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p	n	Positive (%)	p
Sex
Male	77	25 (32.5)	0.581	74	46 (62.2)	0.317	77	62 (91.9)	0.159	71	47 (76.7)	0.523^a
Female	40	11 (27.5)		40	21 (52.5)		40	34 (82.4)		38	22 (86.4)
Age (years)
≤45	10	3 (30.0)	1.000^a	8	4 (50.0)	0.715^a	9	8 (75.0)	0.228^a	8	5 (40.0)	0.053^a
>45	107	33 (30.8)		106	63 (59.4)		108	88 (89.8)		101	64 (82.8)
Presentation
Asymptomatic	19	6 (31.6)	0.933	18	8 (44.4)	0.178	22	18 (88.9)	1.000^a	16	10 (60.0)	0.109^a
Symptomatic	98	30 (30.6)		96	59 (61.5)		95	78 (88.5)		93	59 (83.1)
Localization
Colon	94	28 (29.8)	0.642	91	58 (63.7)	0.032	95	81 (88.9)	0.681^a	88	57 (80.7)	0.698^a
Rectum	23	8 (34.8)		23	9 (39.1)		22	15 (86.7)		21	12 (75.0)
Macroscopic Appearence
Polypoid	47	14 (29.8)	0.596	47	27 (57.4)	0.534	45	36 (86.1)	0.701	45	25 (84.0)	0.500
Ulcerative	31	7 (22.6)		30	20 (66.7)		34	28 (85.7)		28	20 (70.0)
Infiltrative	13	5 (38.5)		13	6 (46.2)		12	11 (90.9)		11	6 (100.0)
Exophytic	14	6 (42.9)		13	7 (53.8)		14	12 (100.0)		14	11 (81.8)
Vilosous	1	0 (0.0)		1	0 (0.0)		1	1 (100.0)		1	1 (100.0)
CEA (ng/mL)
<5	71	21 (29.6)	0.354	67	42 (62.7)	0.434	68	56 (91.1)	0.120	65	40 (85.0)	0.237^a
≥5	25	5 (20.0)		26	14 (53.8)		26	23 (78.3)		23	13 (69.2)

^aComparisons were examined for statistical significance using Fisher’s exact test (when n < 5)