Table 7.
MCT1 | MCT4 | CD147 | GLUT1 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | Positive (%) | p | n | Positive (%) | p | n | Positive (%) | p | n | Positive (%) | p | |
Tumor size (cm) | ||||||||||||
≤4.5 | 67 | 26 (38.8) | 0.065 | 65 | 38 (58.5) | 0.692 | 68 | 53 (92.5) | 0.492a | 65 | 43 (76.7) | 0.548a |
>4.5 | 45 | 10 (22.2) | 45 | 28 (62.2) | 45 | 40 (87.5) | 40 | 25 (84.0) | ||||
Histological Type | ||||||||||||
Adenocarcinoma | 92 | 32 (34.8) | 0.287 | 92 | 54 (58.7) | 0.376 | 90 | 76 (88.2) | 0.826a | 85 | 58 (77.6) | 0.084a |
A. Mucinous | 16 | 2 (12.5) | 15 | 7 (46.7) | 18 | 14 (85.7) | 17 | 6 (100.0) | ||||
A. Invasive | 6 | 1 (16.7) | 6 | 5 (83.3) | 6 | 5 (100.0) | 6 | 4 (100.0) | ||||
Signet ring and mucinous | 3 | 1 (33.3) | 1 | 1 (100.0) | 3 | 1 (100.0) | 1 | 1 (0.0) | ||||
Differentiation | ||||||||||||
Well-differentiated | 41 | 18 (43.9) | 0.152 | 40 | 23 (57.5) | 0.493 | 41 | 36 (91.7) | 0.033a | 38 | 26 (76.9) | 0.902a |
Moderately-differentiated | 51 | 13 (25.5) | 50 | 28 (56.0) | 50 | 43 (86.0) | 47 | 29 (79.3) | ||||
Poorly-differentiated | 23 | 5 (21.7) | 22 | 15 (68.2) | 23 | 16 (93.8) | 22 | 13 (84.6) | ||||
Undifferentiated | 1 | 0 (0.0) | 1 | 0 (0.0) | 2 | 1 (0.0) | 1 | 1 (100.0) | ||||
Tumour Penetration | ||||||||||||
T1 | 2 | 0 (0.0) | 0.408 | 1 | 0 (0.0) | 0.034 | 2 | 1 (100.0) | 0.665a | 1 | 1 (100.0) | 0.653a |
T2 | 5 | 2 (40.0) | 4 | 3 (75.0) | 4 | 3 (100.0) | 4 | 3 (66.7) | ||||
T3 | 101 | 22 (32.7) | 99 | 62 (62.6) | 101 | 83 (89.2) | 96 | 61 (78.7) | ||||
T4 | 9 | 1 (11.1) | 10 | 2 (20.0) | 10 | 9 (77.8) | 8 | 4 (100.0) | ||||
Spread to lymph nodes | ||||||||||||
Absent | 9 | 4 (44.4) | 0.450a | 8 | 6 (75.0) | 0.465a | 10 | 8 (87.5) | 1.000a | 8 | 6 (100.0) | 0.326a |
Present | 96 | 28 (29.2) | 94 | 54 (57.4) | 96 | 77 (89.6) | 90 | 55 (76.4) | ||||
Vessel invasion | ||||||||||||
Absent | 30 | 12 (40.0) | 0.259 | 29 | 20 (69.0) | 0.288 | 33 | 28 (89.3) | 1.000a | 30 | 16 (81.3) | 1.000a |
Present | 80 | 23 (28.8) | 78 | 45 (57.7) | 79 | 62 (88.7) | 73 | 49 (81.6) | ||||
TNM | ||||||||||||
Stage III | 84 | 28 (33.3) | 0.338 | 82 | 52 (63.4) | 0.107 | 82 | 66 (92.4) | 0.076 | 79 | 48 (81.3) | 0.632 |
Stage IV | 33 | 8 (24.2) | 32 | 15 (46.9) | 35 | 30 (80.0) | 30 | 21 (76.2) |
aComparisons were examined for statistical significance using Fisher’s exact test (when n < 5)