Table 1.
Pediatric classic Kaposi’s sarcoma in literature review
| Variable | KS with skin lesion | KS with no skin lesion | Total | ||
|---|---|---|---|---|---|
| number = 32 | number = 4 | ||||
| Origin | Mediterranean Basin | Other countries | Mediterranean Basin | Other countries | |
| 22 | 10 | 2 | 2 | 36 | |
| Age | |||||
| 0- < 10 | 11 | 7 | 1 | 2 | 21 |
| 10- < =15 | 8 | 3 | 1 | 0 | 12 |
| NA | 3 | 0 | 0 | 3 | |
| Sex | |||||
| Male | 15 | 8 | 2 | 2 | 27 |
| Female | 6 | 1 | 0 | 0 | 7 |
| NA | 1 | 1 | 0 | 0 | 2 |
| Clinical findings | |||||
| Lymph node (s) | |||||
| Yes | 10 | 1 | 0 | 2 | 13 |
| No | 2 | 5 | 0 | 0 | 7 |
| NA | 10 | 4 | 2 | 0 | 16 |
| Visceral involvement | |||||
| Yes | 8 | 3 | 1 | 2 | 14 |
| No | 6 | 4 | 1 | 0 | 11 |
| NA | 8 | 3 | 0 | 0 | 11 |
| Diagnosis | |||||
| Skin biopsy | 18 | 8 | 0 | 0 | 26 |
| Lymph node biopsy | 1 a | 0 | 1 | 2 | 3 |
| NA | 4 | 2 | 1 | 0 | 7 |
| HHV-8 status | |||||
| Positive | 12 | 2 | 0 | 0 | 14 |
| Negative | 1 b | 0 | 0 | 0 | 1 |
| Non-conclusive | 1 | 0 | 0 | 0 | 1 |
| Test not yet available (old reports) | 8 | 8 | 2 | 2 | 20 |
| Immunity status | |||||
| Identified Immunodeficiency | 5 | 0 | 0 | 0 | 5 |
| 1- IFN-gamma-R1 deficiency | 2 | 0 | 0 | 0 | |
| 2- Wiskott-Aldrich syndrome | 2 | 0 | 0 | 0 | |
| 3- Inherited human OX40 deficiency | 1 | 0 | 0 | 0 | |
| Unidentified Immunodeficiency | 2 | 2 | 0 | 0 | 4 |
| NA | 15 | 8 | 2 | 2 | 27 |
| Treatment | |||||
| Given treatment | 21 | ||||
| No treatment | 1 | 1 | 0 | 0 | 2 |
| NA | 6 | 5 | 2 | 0 | 13 |
| Outcome | |||||
| Survived | 10 | 5 | 0 | 1 | 16 |
| Dead | 6 | 1 | 1 | 1 | 9 |
| NA | 6 | 4 | 1 | 0 | 11 |
HHV-8 Human herpes virus-8, IFN Interferon, KS Kaposi’s sarcoma, NA not available
aOne case with skin and lymph node biopsy
b(reference 18, 1999)