TABLE III.
Univariate analysis
|
Multivariate analysis
|
|||
---|---|---|---|---|
HR (95%CI) | P-value | HR (95%CI) | P-value | |
Gender | 0.893 | |||
Female | Ref. | |||
Male | 0.96 (0.50–1.81) | |||
Age | 0.347 | |||
<50 years | Ref. | |||
≥50 years | 0.99 (0.97–1.01) | |||
ASA physical status | 0.092 | |||
1–2 | Ref. | |||
3–4 | 2.13 (0.88–5.17) | |||
Coronary artery disease | 0.205 | |||
No | Ref. | |||
Yes | 1.86 (0.71–4.87) | |||
Chronic heart failure | 0.309 | |||
No | Ref. | |||
Yes | 0.35 (0.05–2.61) | |||
Chronic obstructive pulmonary disease | 0.164 | |||
No | Ref. | |||
Yes | 1.95 (0.76–5.05) | |||
Chronic renal insufficiency | 0.074 | |||
No | Ref. | |||
Yes | 3.86 (0.88–17.0) | |||
Diabetes mellitus | 0.002 | |||
No | Ref. | |||
Yes | 3.36 (1.55–7.28) | |||
Incidentaloma | 0.788 | |||
No | Ref. | |||
Yes | 0.92 (0.48–1.74) | |||
Functional status | 0.229 | |||
No | Ref. | |||
Yes | 1.50 (0.77–2.93) | |||
Tumor size | 0.987 | |||
≤5 cm | Ref. | |||
>5 cm | 0.99 (0.78–1.26) | |||
Preoperative chemo-radiotherapy | 0.149 | |||
No | Ref. | |||
Yes | 2.91 (0.68–12.5) | |||
Other organ resected | 0.074 | |||
No | Ref. | |||
Yes | 1.79 (0.94–3.41) | |||
IVC exclusion | 0.064 | |||
No | Ref. | |||
Yes | 2.51 (0.95–6.63) | |||
AJCC tumor status | <0.001 | |||
T stages I–II | Ref. | Ref. | ||
T stages III–IV | 4.54 (2.07–9.99) | 3.91 (1.76–8.73) | 0.001 | |
AJCC node status | 0.008 | |||
N0 | Ref. | |||
N1 | 1.63 (1.13–2.35) | |||
AJCC metastasis status | 0.004 | 0.028 | ||
M0 | Ref. | Ref. | ||
M1 | 2.84 (1.39–5.79) | 2.42 (1.10–5.35) | ||
Margin status | <0.001 | |||
R0 | Ref. | |||
R1/R2 | 3.83 (1.88–7.77) | |||
Complications | 0.004 | |||
No | Ref. | |||
Yes | 2.90 (1.40–6.01) | |||
Readmission within 90 days | 0.039 | |||
No | Ref. | |||
Yes | 2.06 (1.03–4.09) | |||
NLR | 0.002 | 0.025 | ||
≤5 | Ref. | Ref. | ||
>5 | 2.85 (1.49–5.47) | 2.21 (1.10–4.43) | ||
PLR | 0.757 | |||
≤190 | Ref. | |||
>190 | 0.90 (0.47–1.73) | |||
Post-operative chemotherapy | 0.438 | |||
Not performed | Ref. | |||
Performed | 1.42 (0.58–3.52) | |||
Post-operative radiotherapy | 0.893 | |||
Not performed | Ref. | |||
Performed | 1.07 (0.37–3.07) | |||
Post-operative chemotherapy with mitotane | 0.372 | |||
Not performed | Ref. | |||
Performed | 1.38 (0.67–2.81) |
IVC, inferior vena cava; P-values ≤ 0.05 are reported in bold and indicate statistically significant results.