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. Author manuscript; available in PMC: 2017 Mar 29.
Published in final edited form as: Stress. 2016 Mar 29;19(2):235–247. doi: 10.3109/10253890.2016.1160280

Figure 6. Effects of 3-PBC in the CeA and mPFC on delay discounting, operant binge drinking, and sucrose drinking.

Figure 6

(A) Both 20 and 40 μg doses of 3-PBC microinjected into the CeA, elevated adjusted amounts [decreased impulsivity] in MS rats [N=5/dosage group] compared to vehicle treatment [N=5]. (B) Both doses of 3-PBC also reduced operant responding of MS rats [N=5/dosage group] for alcohol compared to vehicle [N=5]. (C) Neither dose of 3-PBC in the CeA [N=5/dosage group] altered the responding of MS rats for sucrose compared to vehicle [N=5]. (D) The 40 μg dose of 3-PBC microinjected into the mPFC, elevated adjusted amount [decreased impulsivity] in MS rats [N=4] compared to vehicle treatment [N=4]. (E) 40 μg of 3-PBC also reduced operant responding of MS rats [N=4] for alcohol compared to vehicle [N=4]. (F) 3-PBC in the mPFC [N=5] did not alter the responding of MS rats for sucrose compared to vehicle [N=5]. * P ≤ 0.05 by ANOVA.