Table 1.
Molecular motor–adaptor complexes and regulators of mitochondrial transport
| Protein | Role | Organism(s) | Refs |
|---|---|---|---|
| KIF5 | Microtubule motor | Drosophila melanogaster and mammals | 35,37,40,41 |
| KIF1Bα | Microtubule motor | Mammals | 42 |
| KLP6 | Microtubule motor | Mammals | 43 |
| Dynein–dynactin | Microtubule motor | D. melanogaster and mammals | 37,60 |
| MIRO | KIF5 receptor | D. melanogaster and mammals | 45–47,49 |
| Milton | KIF5 adaptor | D. melanogaster | 36,44,48 |
| TRAKs (OIP106, GRIF1) | KIF5 adaptor | Mammals | 46,50,51,55,56 |
| Syntabulin | KIF5 adaptor | Mammals | 41 |
| FEZ1 | KIF5 adaptor | Mammals | 57,58 |
| RANBP2 | KIF5 adaptor | Mammals | 59 |
| APLIP1 | KIF5 adaptor | D. melanogaster | 69 |
| Syntaphilin | Static anchor | Mammals | 12,81 |
| Mitofusins | MIRO–TRAK regulator | Mammals | 70 |
| Tau | Microtubule stability | Mammals | 93 – 99 |
| MAP1B | Microtubule stability | Mammals | 100 |
| Myosin XIX | Actin motor | Mammals | 72 |
| Myosin V | Actin motor | D. melanogaster neurons | 75 |
| Myosin VI | Actin motor | D. melanogaster neurons | 75 |
| WAVE1 | Actin polymerization | Mammals | 82 |
APLIP1, APP-like-interacting protein1; FEZ1, fasciculation and elongation protein-ζ1; KIF, kinesin superfamily protein; MAP1B, microtubule-associated protein 1B; MIRO, Mitochondrial rho; RANBP2, RAN-binding protein 2; WAVE1, WASP family verprolin homologous protein 1.