Table 1.
Nanotechnology that is applicable for osteoarthritis research.
| Nanotechnology | Size | Type of therapy | Targeting/activation method | Detection method | Ref. |
|---|---|---|---|---|---|
| Liposome | 5–200 nm | Diagnostic and therapeutic | Antibody | Fluorescence | [15,22–24,32] |
| Micellar nanocarrier | 46 nm | Therapeutic | Proteolytic | – | [18,38] |
| HDL nanodisc | 5–100 nm | Diagnostic and therapeutic | Protein/peptide, antibody targeting | MRI | [55,57–59] |
| Quantum dot (and constructs) | ~0.9–18.2 nm | Diagnostic and therapeutic | Proteolytic | FRET, fluorescence | [19,21,62–65] |
| Magnetic nanoparticles | ~30 nm–1 μm | Diagnostic and therapeutic | Magnetic | MRI, PET | [67–74,76–78] |
FRET: Fluorescence resonance energy transfer.