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. Author manuscript; available in PMC: 2017 Apr 13.
Published in final edited form as: Nano Lett. 2016 Apr 5;16(4):2556–2559. doi: 10.1021/acs.nanolett.6b00108

Figure 1.

Figure 1

(a) LANDs consist of a perfluorohexane core with encapsulated optical trigger (e.g., dye) and a stabilizing shell. (b) LANDs are vaporized by a pulsed laser irradiation (left). In their transient microbubble state, acoustic waves are reflected, providing ultrasound contrast. The LANDs recondense one at a time after the vaporization and no longer produce ultrasound contrast. (c) Ultrasound images before the laser trigger, immediately following the laser pulse, 30 ms after the laser pulse, and 60 ms after the laser pulse (from left to right) show the blinking behavior of LANDs.