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(a) B-mode ultrasound imaging of a mouse brain (gray scale) with overlaid signal corresponding to blinking pixels (green). (b) After the super-resolution algorithm is applied to the images, the precise locations of the LANDs are determined, and finer details emerge. (c–d) Two small clusters of localized LANDs (corresponding to the orange and blue boxes in b, respectively) show that an axial resolution of 8 μm and a lateral resolution of 16 μm can be achieved in vivo.
