Table 3.

Hazard Ratios Associated with Selected Risk factors for Endometrial Cancer, BRCA1 carriers only

Variables	Univariate OR (95%CI) P-value	Multivariate OR (95%CI) P-value
Age at baseline questionnaire	0.94 (0.87–1.00) 0.06	0.96 (0.89–1.04) 0.33
Parity (mean)	0.85 (0.67–1.06) 0.15	0.85 (0.67–1.08) 0.18
Tamoxifen (any use)
No	1	1
Yes	4.49 (1.79–11.3) 0.001	3.66 (1.44–9.31) 0.006
Tamoxifen
Breast cancer
patients only
No	1	1
Yes	6.60 (2.22 – 19.5) 0.0007	7.19 (2.11–24.5) 0.002
Menopausal status
Premenopausal	1	1
Postmenopausal	1.04 (0.47–2.34) 0.92	1.07 (0.45–2.57) 0.87
HRT
No	1	1
Yes	1.04 (0.44–2.47) 0.93	0.85 (0.32–2.30) 0.75
E	0.48 (0.06–3.66) 0.48	0.52 (0.06–4.23) 0.54
P	7.44 (1.19–46.4) 0.03	16.5 (2.02–134) 0.009
EP	1.30 (0.44–3.83) 0.63	1.77 (0.20–2.98) 0.70
Oral contraceptives
Never	1	1
Ever	1.34 (0.65–2.74) 0.43	1.23 (0.56–2.69) 0.61
Smoking history
Never	1	1
Ever	1.41 (0.78–2.55) 0.26	1.23 (0.66–2.28) 0.51
BMI18	1.01 (0.93–1.09) 0.82	1.00 (0.90–1.11) 0.95
BMI30	1.01 (0.93–1.09) 0.80	1.08 (0.94–1.24) 0.27
BMI40	0.98 (0.91–1.05) 0.55	0.94 (0.83–1.05) 0.28