TABLE 5.

Variables Predicting the Presence of RV-PV Dysfunction

	Model 1		Model 2		Model 3
	C-Statistic	p Value	C-Statistic	p Value	C-Statistic	p Value
Model without metabolites	0.68		0.72		0.82
Kynurenine	0.76	0.007	0.80	0.004	0.86	0.03
Quinolinate	0.72	0.05	0.75	0.07	0.85	0.13
Anthranilate	0.71	0.11	0.74	0.10	0.87	0.01
Kynurenate	0.75	0.04	0.79	0.01	0.88	0.02
IDO score	0.74	0.01	0.79	0.006	0.87	0.01

Model 1: Consists of readily available clinical variables associated with pulmonary hypertension (age, sex, body mass index). Model 2: Adds pulmonary artery wedge pressure to model 1 variables. Model 3: Adds measured right ventricular ejection fraction; omits body mass index based on lack of significant association with any of the metabolite levels or pulmonary hypertension.

Abbreviations as in Table 2.