FIG 1.

FICs in healthy adults at stage 1 (before or within 48 h of a challenge) and outcomes of a challenge with Cryptosporidium oocysts. (A) Cumulative percent infection was calculated as described previously (40) and plotted against the mean indole concentration. The number of subjects at each indole concentration stratum is in parentheses. (B) The indole concentrations and outcome categories of the subjects are shown. The mean indole concentration ± the standard error of the mean are indicated for the infected (oocysts plus diarrhea; n = 18) and uninfected (no oocysts or diarrhea; n = 32) challenge outcome groups. Outcome groups were compared by using the Mann-Whitney test (P = 0.0001).