TABLE 2.
Numbers of subjects in the study population in different age, sex, and ethnicity groupsa
| Characteristic | No. (%) of subjects |
Mean baseline indole concn (mM) ± SD | |
|---|---|---|---|
| Uninfectedb | Infectedc | ||
| Total | 32 (64.0) | 18 (36.0) | |
| Age (yr) | |||
| <20 | 0 (0.0) | 1 (5.6) | 1.36 |
| 20–29 | 16 (50.0) | 9 (50.0) | 2.74 ± 1.55 |
| 30–39 | 8 (25.0) | 4 (22.2) | 2.31 ± 1.07 |
| >40–50 | 8 (25.0) | 4 (22.2) | 2.84 ± 0.99 |
| Sex | |||
| Male | 15 (46.9) | 8 (44.4) | 2.65 ± 1.55 |
| Female | 17 (53.1) | 10 (65.6) | 2.64 ± 1.14 |
| Ethnicity | |||
| Caucasian | 15 (46.9) | 9 (50.0) | 2.70 ± 1.49 |
| Black | 10 (31.3) | 4 (22.2) | 2.84 ± 0.91 |
| Hispanic/Asian | 7 (21.9) | 5 (27.8) | 2.30 ± 1.35 |
| Challenge species/isolate | |||
| C. parvum | 26 (81.3) | 15 (83.3) | 2.57 ± 1.41 |
| C. hominis | 6 (18.8) | 3 (16.7) | 2.96 ± 0.73 |
a
Total n = 50. Volunteers were challenged with C. parvum or C. hominis and monitored for outcomes (no oocysts or diarrhea, oocysts plus diarrhea). One Asian subject was grouped with Hispanic volunteers. Mean FICs and standard deviations were measured in stool samples collected before or within 48 h of the challenge.
b
No oocysts or diarrhea.
c
Oocysts plus diarrhea.