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NSG mice infected with CLH001 showed 100% survival and complete bacterial clearance. (A) Percent survival of NSG mice following i.n challenge with 1.5 × 104 CFU of CSM001 (n = 4, ●) or CLH001 (n = 6, ▲) at 21 days postinfection. (B) Colonization of mouse lungs, livers, and spleens (n = 4) at day 21 postinfection with 1.5 × 104 CFU of CLH001 (■). The limit of detection was 10 CFU/organ (horizontal dotted line).
