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CLH001 serum promotes killing of B. mallei 23344 in vitro. Serum bactericidal assays were performed by incubating 1.0 ×105 CFU of B. mallei 23344 and guinea pig complement plus heat-inactivated naive sera, heat-inactivated CLH001 sera, or anti-B. mallei LPS monoclonal antibody. After 6 h, samples were serially diluted and plated to determine CFU counts per milliliter. Experiments were performed in triplicate.
