Table 1.
Projected HAV cases by presence of symptoms and resource use, and projected costs, for each vaccination strategy
Projected HAV cases/costs | No vaccination | Single dose | Two doses |
---|---|---|---|
Total HAV infections | 46,841,960 | 20,188,993 | 15,494,178 |
Anicteric infections | 31,664,073 | 10,456,707 | 8,723,659 |
Asymptomatic | 15,832,057 | 5,228,353 | 4,361,830 |
Symptomatic | 15,832,057 | 5,228,353 | 4,361,830 |
Without medical resource use | 7,916,018 | 2,614,177 | 2,180,915 |
With medical resource use | 7,916,018 | 2,614,177 | 2,180,915 |
Icteric infections | 15,177,887 | 9,732,286 | 6,770,519 |
Not reported | 14,154,963 | 9,076,373 | 6,314,215 |
Without medical resource use | 758,894 | 486,614 | 338,526 |
With medical resource use | 13,396,069 | 8,589,758 | 5,975,689 |
Reported | 1,022,924 | 655,914 | 456,304 |
Outpatient care only | 963,667 | 612,780 | 425,919 |
Hospitalisation | 53,153 | 38,780 | 26,966 |
Fulminant hepatitis | 6,103 | 4,354 | 3,419 |
Alive after liver transplant | 275 | 201 | 158 |
Alive without liver transplant | 2,119 | 1,506 | 1,181 |
Death | 3,710 | 2,647 | 2,080 |
Costs, base case (MXN) | |||
Medical treatment costs | 12,556,191,424 | 7,855,880,009 | 6,275,142,125 |
Vaccination costs | Not applicable | 5,098,632,701 | 9,432,470,554 |
Total | 12,556,191,424 | 12,954,512,710 | 15,707,612,679 |
Costs, societal perspective (MXN) | |||
Medical treatment costs | 12,556,191,424 | 7,855,880,009 | 6,275,142,125 |
Indirect costs | 4,178,903,736 | 2,185,832,885 | 1,817,758,851 |
Vaccination costs | Not applicable | 5,098,632,701 | 9,432,470,554 |
Total | 16,735,095,160 | 15,140,345,595 | 17,525,371,530 |
HAV, hepatitis A virus; MXN, Mexican peso. Data on costs are discounted.