Extended Data Figure 9. Glial cell sensing via MYD88 signals.
a-c, Intestinal glial cells were purified by flow cytometry. a, Germ-free (GF) and their respective Specific Pathogen Free (SPF) controls. n=3. b, Myd88-/- and their respective WT littermate controls. n=3. c, Gfap-Cre.Myd88Δ and their littermate controls (Myd88fl). n=3. d, Total lamina propria cells of Gfap-Cre.Myd88Δ and their littermate controls (Myd88fl). n=6. e-h, Citrobacter rodentium infection of Gfap-Cre.Myd88Δ mice and their littermate controls (Myd88fl). n=6. e, Innate IL-22. f, Citrobacter rodentium translocation. g, Infection burden. h, Weight loss. Data are representative of 3 independent experiments. Error bars show s.e.m. *P<0.05; **P<0.01; ns not significant.
