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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Acta Neurochir Suppl. 2016;122:255–260. doi: 10.1007/978-3-319-22533-3_51

Table 1.

Monitored variables

ICP, MAP and CPP, mmHg Cortical Doppler flux, % of baseline iPRx iCVRx MVS/CAP ratio NADH, ΔF/Fo BBB damage, ΔF/Fo
ICP 10 / MAP 80 / CPP 70 100.1 ± 9.3 −0.03 ± 0.07 −0.02 ± 0.09 0.41 ± 0.14 0.02 ± 0.09 0.01 ± 0.34
ICP 30 / MAP 80 / CPP 50 98.3 ± 9.4 0.24 ± 0.09* 0.31 ± 0.13* 0.72 ± 0.15* 0.28 ± 0.11* 2.24 ± 075**
ICP 50 / MAP 80 / CPP 30 71.2 ± 10.5* 0.33 ± 0.11** 0.46 ± 0.14** 1.1 ± 0.18** 0.59 ± 0.14** 3.89 ± 0.98***

ICP, intracranial pressure; MAP, mean arterial pressure; CPP, cerebral perfusion pressure; iPRx, induced intracranial pressure reactivity; iCVRx, induced cerebrovascular reactivity; MVS/CAP, microvascular shunt flow/capillary flow ratio; BBB, blood brain barrier. N= 10 rats, Mean ± SEM

*

=p<0.05

**

=p<0.01

**

=p<0.001. Data are compared with baseline CPP of 70 mmHg.