Table 2.
Comparison of the average number of reinforcers earned by rats trained to self-administer IV saline over daily 1-h sessions (Saline), cocaine over daily 6-h sessions (Cocaine) or to self-administer sucrose pellets over daily 6-h sessions (Sucrose) that were slated to receive an intra-dmPFC infusion of DMSO vehicle or 1.0 µg/side ifenprodil. The numbers represent the means ± SEMs of the number of animals indicated in parentheses.
| Vehicle | Ifenprodil | |
|---|---|---|
| Saline | 11 ± 3.4 (6) | 6.9 ± 1.4 (7) |
| Sucrose | 123.1 ± 21.4 (7)+ | 146.0 ± 29.0 (5)+ |
| Cocaine | 110.3 ± 9.0 (10)+ | 161.2 ± 42.5 (10)+ |
p<0.05 vs. Saline (LSD post-hoc tests)