Figure 3.

Bibliometric map automatically created with Visualization of Similarity (VOS) viewer. Scientific terms are clustered with respect to their co-occurrence in title and abstract of PubMed references, which are published over the last 3 y (2013/01/01 - 2015/08/14) with ‘vaccination’, ‘vaccine’, ‘humoral immune response’, ‘single nucleotide polymorphism(s)’ or ‘SNP(s)' in title. Term proximity reflects co-occurrence and term size reflects occurrence frequency. Genetic terms (blue cluster) overlap with cancer terms (yellow cluster) and show close proximity to immunobiological terms (green cluster). In contrast, clinical and vaccination terms (red cluster) are almost separated from genetic terms. Bridging terms are for instance ‘liver transplantation’, ‘chronic hepatitis' and ‘ethnicity’. In total, 4,366 terms from 16,658 references are clustered.