Table 1.
Levels of antigen-specific IgA antibody responses at systemic and mucosal sites.
| Gastrointestinal Tract |
Respiratory Tract |
Reproductive Tract |
||||||
|---|---|---|---|---|---|---|---|---|
| Delivery route | Saliva | Intestine | Feces | Upper | Lower | Vagina | Uterus | Serum |
| i.p. | −(21,23,24,26) + (16,20) | ++ (18,20,26) | + (26) ++(28) +++ (27) | −(18,20,21,24,25) +(26) ++(27) +++(17) | +(18,26,28) ++(20) | +++(27) | −(27,28) +(18,23) | |
| i.m. | +(33) ++(35) | ++(47) | +(37) ++(32,47) | −(55) ++(34,35) +++(38) | −(30,38,41,50) +(36,47,49) ++(34) | +(31) | −(34) +(31,36,37) ++(47) +++(38) | |
| s.c. | ++(68) | +(59) ++(58) +++(61) | −(64,65,66) +(68) | ++(60) | −(56,57,63,67) | −(62) +(68) ++(59) | −(57,62,63,66,67) ++(59,60,68) +++(61) | |
| i.d. | −(76,77,78) +++(72) | −(79) | −(76,77) ++(69,71) | ++(70,73) | +++(72) | −(76,78) +(73,77) ++(74) | ||
| TC | +(86) ++(97) | +(88) ++(86) | −(90) +(88) ++(80,81,97) | +(86) | +(83) | +(85,97) ++(86) | −(90) +(84,88,97) ++(80,82) | |
Levels were scored as none (−), slight (+), moderate (++), or strong (+++) based on the primary publication. The numbers in the parenthesis refer to the citations in the References.