Table 3. Distributions of genotypic frequencies of ADAMTS14 SNPs in controls and oral cancer patients.
| Variable | Controls (N = 1200) n (%) | Patients (N = 850) n (%) | OR (95% CI) | AOR (95% CI) |
|---|---|---|---|---|
| rs10823607 | ||||
| CC | 1017 (84.7%) | 714 (84.0%) | 1.00 | 1.00 |
| CT | 175 (14.6%) | 132 (15.5%) | 1.07 (0.84–1.37) | 1.03 (0.74–1.42) |
| TT | 8 (0.7%) | 4 (0.5%) | 0.71 (0.21–2.37) | 0.80 (0.15–4.18) |
| CT+TT | 183 (15.3%) | 136 (16.0%) | 1.06 (0.83–1.35) | 1.02 (0.74–1.40) |
| rs12774070 | ||||
| CC | 876 (73.0%) | 616 (72.5%) | 1.00 | 1.00 |
| CA | 290 (24.2%) | 219 (25.8%) | 1.07 (0.88–1.32) | 1.06 (0.81–1.39) |
| AA | 34 (2.8%) | 15 (1.8%) | 0.63 (0.34–1.16) | 0.47 (0.21–1.07) |
| CA+AA | 324 (27.0%) | 234 (27.5%) | 1.03 (0.84–1.25) | 0.99 (0.76–1.29) |
| rs4747096 | ||||
| AA | 489 (40.8%) | 360 (42.4%) | 1.00 | 1.00 |
| AG | 568 (47.3%) | 384 (45.2%) | 0.92 (0.76–1.11) | 1.00 (0.78–1.29) |
| GG | 143 (12.0%) | 106 (12.5%) | 1.01 (0.76–1.34) | 1.19 (0.81–1.75) |
| AG+GG | 711 (59.3%) | 490 (57.6%) | 0.94 (0.78–1.12) | 1.04 (0.82–1.32) |
| rs61573157 | ||||
| CC | 995 (82.9%) | 702 (82.6%) | 1.00 | 1.00 |
| CT | 194 (16.2%) | 141 (16.6%) | 1.03 (0.81–1.31) | 1.03 (0.75–1.41) |
| TT | 11 (0.9%) | 7 (0.8%) | 0.90 (0.35–2.34) | 1.31 (0.36–4.85) |
| CT+TT | 205 (17.1%) | 148 (17.4%) | 1.02 (0.81–1.29) | 1.04 (0.76–1.42) |
The odds ratio (OR) with their 95% confidence intervals were estimated by logistic regression models.
The adjusted odds ratio (AOR) with their 95% confidence intervals were estimated by multiple logistic regression models after controlling for betel nut chewing, alcohol and tobacco consumption.