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. Author manuscript; available in PMC: 2016 Jul 27.

Published in final edited form as: Phys Med Biol. 2013 Jun 4;58(12):4277–4296. doi: 10.1088/0031-9155/58/12/4277

The individual percentage changes in FA, MD, AD, and RD in the cingulum (a), the fornix (b), and the corpus callosum (c) in the patients who underwent PBRT from pre-RT to week 3 during RT (3 W, circle), end of RT (6 W, plus), 1 month (1 M, downward-pointing triangle), 6 months (6 M, square) and 18 months (18 M, upward-pointing triangle) after RT. TC indicates the percentage of the patients who had changes beyond the uncertainty. The lines show the estimated –RC_U and RC_L (minus upper limit and lower limit of RC), respectively. If a diffusion index percentage change is larger than RC_L or smaller than –RC_U, we consider it a true change.

The individual percentage changes in FA, MD, AD, and RD in the cingulum (a), the fornix (b), and the corpus callosum (c) in the patients who underwent PBRT from pre-RT to week 3 during RT (3 W, circle), end of RT (6 W, plus), 1 month (1 M, downward-pointing triangle), 6 months (6 M, square) and 18 months (18 M, upward-pointing triangle) after RT. TC indicates the percentage of the patients who had changes beyond the uncertainty. The lines show the estimated –RC_U and RC_L (minus upper limit and lower limit of RC), respectively. If a diffusion index percentage change is larger than RC_L or smaller than –RC_U, we consider it a true change.