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Metabolic inhibition selectively eliminates MDA-MB-231 cancer cells. The graphs show mean values ± SEM (N = 7 per condition) of fold-change in cancer cell bioluminescence and drug selectivity in spheroids composed of MDA-MB-231 cancer cells and HS-5 or HS-27A stromal cells treated with 2-deoxy-glucose (A), dichloroacetate (B), oligomycin (C), rotenone (D), DHEA (E), or PD0325901 (F).
