Table 4.

Multivariate model predicting rotavirus vaccination compliance by PI guidelines¹.

Variable	Relative risk	95% CI	p-value
Sex
Male	REF
Female	1.006	0.998 – 1.014	0.144
Health insurance type
Other/Unknown	REF
FFS	1.388	1.366 – 1.410	<0.001
Provider specialty
Pediatric	REF
Family practice	0.917	0.901 – 0.934	<0.001
General practice	0.957	0.937 – 0.978	<0.001
Other	0.912	0.896 – 0.927	<0.001
Unknown	0.905	0.894 – 0.916	<0.001
Completion of DTaP vaccination
Non-completion of DTaP	REF
Completion of DTaP	11.816	11.560 – 12.078	<0.001
Vaccine type and birth year interaction
RV1 in birth year 2008 vs. RV5 in birth year 2008	2.016	1.914 – 2.125	<0.001
RV1 in birth year 2009 vs. RV5 in birth year 2009	2.238	2.200 – 2.276	<0.001
RV1 in birth year 2010 vs. RV5 in birth year 2010	2.200	2.167 – 2.234	<0.001
RV1 in birth year 2011 vs. RV5 in birth year 2011	2.319	2.285 – 2.354	<0.001
RV1 in birth year 2012 vs. RV5 in birth year 2012	2.735	2.665 – 2.807	<0.001
RV5 in birth year 2009 vs. RV5 in birth year 2008	0.976	0.961 – 0.992	0.004
RV5 in birth year 2010 vs. RV5 in birth year 2008	1.016	1.000 – 1.032	0.049
RV5 in birth year 2011 vs. RV5 in birth year 2008	0.975	0.959 – 0.991	0.003
RV5 in birth year 2012 vs. RV5 in birth year 2008	1.130	1.105 – 1.156	<0.001
Race and state interaction
Black infants in FL vs. white infants in FL	0.890	0.874 – 0.906	<0.001
Hispanic infants in FL vs. white infants in FL	0.999	0.983 – 1.015	0.863
Other/unknown infants in FL vs. white infants in FL	1.020	0.999 – 1.041	0.060
Black infants in IA vs. white infants in IA	0.871	0.809 – 0.938	<0.001
Hispanic infants in IA vs. white infants in IA	0.967	0.918 – 1.018	0.199
Other/unknown infants in IA vs. white infants in IA	0.977	0.954 – 1.001	0.057
Black infants in KS vs. white infants in KS	0.942	0.912 – 0.973	<0.001
Hispanic infants in KS2 vs. white infants in KS	—	–	—
Other/unknown infants in KS vs. white infants in KS	0.912	0.881 – 0.944	<0.001
Black infants in MS vs. white infants in MS	1.024	1.009 – 1.040	0.002
Hispanic infants in MS vs. white infants in MS	1.010	0.969 – 1.051	0.646
Other/unknown infants in MS vs. white infants in MS	1.039	0.978 – 1.103	0.218
White infants in IA vs. white infants in FL	1.000	0.976 – 1.025	0.969
White infants in KS vs. white infants in FL	1.318	1.290 – 1.347	<0.001
White infants in MS vs. white infants in FL	0.983	0.966 – 1.001	0.057
Black infants in IA vs. black infants in FL	0.979	0.911 – 1.053	0.575
Black infants in KS vs. black infants in FL	1.395	1.346 – 1.447	<0.001
Black infants in MS vs. black infants in FL	1.131	1.110 – 1.153	<0.001
Hispanic infants in IA vs. Hispanic infants in FL	0.968	0.922 – 1.017	0.202
Hispanic infants in KS2 vs. Hispanic infants in FL	—	—	—
Hispanic infants in MS vs. Hispanic infants in FL	0.994	0.954 – 1.035	0.763
Other/unknown infants in IA vs. other/unknown infants in FL	0.958	0.938 – 0.980	<0.001
Other/unknown infants in KS vs. other/unknown infants in FL	1.179	1.134 – 1.225	<0.001
Other/unknown infants in MS vs. other/unknown infants in FL	1.001	0.941 – 1.065	0.972

PI, package insert; RV, rotavirus; RV1, Rotarix™, GSK Vaccines; RV5, RotaTeq, Merck & Co, Inc.; CI, confidence interval; REF, reference; FFS, fee-for-service; DTaP, diphtheria-tetanus-pertussis vaccination; FL, Florida; IA, Iowa; KS, Kansas; MS, Mississippi.

¹Estimates for all combinations of the vaccine type*birth year, and race*state interactions from the multivariate model are presented.

²Kansas claims data did not specifically identify Hispanic individuals.