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. 2016 Jul 27;11(7):e0159667. doi: 10.1371/journal.pone.0159667

Table 3. Costs (per patient) associated with risk factor-based compared to universal MRSA screening.

Cost (CAD) Risk factor-based screening (24 months) Universal screening (20 months) Comments
Previously known MRSA—bacteremia n = 8 n = 14
Laboratory cost $19.92 $149.90 $280.10 Cost of PCR test
Contact precautions /day $68.15 $8,718.09 $16,290.37 Average 17 days
Infection control time $10.27 $77.28 $144.41 For known MRSA case
Private room /day $220.00 $28,143.50 $52,588.14 Average 17 days
Housekeeping $66.69 $501.84 $937.73 Isolation room cleaned on discharge
Length of stay cost /day $1,219.00 $155,940.58 $291,386.10 Average 17 days
Total $1,604.03 $193,531.19 $361,626.84
Previously known MRSA—colonized n = 167 n = 313
Laboratory cost $19.92 $3,336.10 $6,233.74 Cost of PCR test
Contact precautions /day $68.15 $91,307.37 $170,614.34 Average 8 days
Infection control time $10.27 $1,719.97 $3,213.88 For known MRSA case
Private room /day $220.00 $294,756.00 $550,772.64 Average 8 days
Housekeeping $66.69 $11,168.91 $20,869.00 Isolation room cleaned on discharge
Length of stay cost /day $0 $0 $0 No associated length of stay costs
Total $385.03 $402.288.35 $751,704.51
Newly MRSA bacteremia n = 6 n = 12
Laboratory cost $36.51 $207.30 $428.59 PCR positive/culture positive
Contact precautions /day $68.15 $6,578.19 $13,600.22 Average 17 days
Infection control time $20.54 $116.63 $241.12 For new MRSA case
Private room /day $220.00 $21,235.53 $43,903.86 Average 17 days
Lost revenue due to blocked bed $180.00 $1,022.03 $2,113.02 Assumed 1 day per new case
Housekeeping $66.69 $378.66 $782.87 Isolation room cleaned on discharge
Housekeeping cost difference $24.07 $136.67 $282.56 Isolation clean to move patient to private room
Length of stay cost /day $1,219.00 $117,664.16 $243,267.30 Average 17 days
Total $1,834.96 $147,339.17 $304,619.54
Newly MRSA colonized n = 126 n = 261
Laboratory cost $19.92 $2,517.24 $5,204.32 Cost of PCR test
Contact precautions /day $68.15 $68,895.51 $142,439.50 Average 8 days
Infection control time $20.54 $2,595.59 $5,366.30 For new MRSA case
Private room /day $220.00 $222,406.63 $459.819.36 Average 8 days
Lost revenue due to blocked bed $180.00 $22,746.13 $47,026.98 Assumed 1 day per new case
Housekeeping $66.69 $8,427.44 $17,423.50 Isolation room cleaned on discharge
Housekeeping cost difference $24.07 $3,041.66 $6,288.55 Isolation clean to move patient to private room
Length of stay cost /day $0 $0 $0 No associated length of stay costs
Total $599.37 $330,630.20 $683,568.51
False Positive for MRSA n = 71 n = 147
Laboratory cost $23.85 $1,693.35 $3505.95 PCR positive culture negative
Contact precautions /day $68.15 $9,677.30 $20,036.10 For 48 hours until culture confirmed negative
Infection control time $10.27 $729.17 $1,509.69 For false positive case
Private room /day $220.00 $31,240.00 $64,680.00 For 48 hours until culture confirmed negative
Lost revenue due to blocked beds $180.00 $12,780.00 $26,460.00 Assumed 1 day per new case
Housekeeping cost difference $24.07 $1,708.97 $3,538.29 Isolation clean to move patient to private room
Total $526.34 $57,828.79 $119,730.03
All other screens n = 21,893 n = 51,068
Laboratory cost $19.92 $436,108.56 $1,017,274.56 Cost of PCR incurred with negative screens
Total $19.92 $436,108.56 $1,017,274.56
Overall Total $1,567,726.25 $3,238,523.99