Skip to main content
. 2016 Jul 27;11(7):e0160034. doi: 10.1371/journal.pone.0160034

Fig 2. Allelic effect of endogenous PTHrP levels in simulated microgravity, and compensation by exogenous PTHrP 1–36 (6-day experiments).

Fig 2

(A) Microgravity simulation apparatus (RCCS) with one rotating culture unit (HARV). (B) MicroHex carriers with attached trabecular osteoblasts in culture. (C) Cell-induced MicroHex aggregate in culture (occurs for both trabecular and calvarial osteoblasts). (D) Trabecular osteoblast viability after 6 days on MicroHex carriers in normal gravity (1g) or in simulated microgravity (0g) (triplicate 6-day experiments). White bars: untreated; black bars: 2-h daily treatment with PTHrP1-36 10-8M. ** p < 0.01, *** p < 0.001. Scale bars: B, C: 200 μm.