Fig 10. FMRP only partially co-localizes with the ribosomal protein L7 and members of the FXR family.

A) Double-immunofluorescence of FMRP (red) and L7 (green) showing that the majority of L7 does not co-localize with FMRP, while a minority of the latter (B) is free of L7. C) Co-localization of the three FXR protein members in dendritic granules of primary hippocampal neurons. Triple immunofluorescence of FMRP, FXR1P, and FXR2P, showing that all three members are present in dendritic granules, but do not always co-localize. Arrowheads point to granules containing a single FXR protein, presumably at the spines. D) Quantification and distribution of the three FXR protein members in dendritic granules shown in (C).