Table 5.
Analogs in CML cell lines.
| ||||||
|---|---|---|---|---|---|---|
| Compound ID | R1 | R | IC50 AR230 (μm) | IC50 AR230R (μm) | Fold Difference | LogP[a] |
| SH-4-54 | c-Hex | F | 2.9 | 2.6 | - | 4.11 |
| AM-1-124 | t-Bu | H | 26.9 | 4.8 | 5.6 | 4.30 |
[a]
Values calculated by StarDrop.
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