Table 1. p53 regulated miRNA in GI cancer.

miRNA	Wtp53/Mutp53	Transcriptional Target	Tumor Suppressor/ Oncogene	Function	Ref.
miR-26a	Wt	Yes	Tumor Suppressor	↓Proliferation ↓Metastasis ↑Apoptosis	8, 31, 32
miR-34	Wt	Yes	Tumor Suppressor	↓Proliferation, ↑Cell Cycle Arrest, ↑Apoptosis, ↑Senescence, ↓Tumor Sphere Formation, ↓EMT	9, 28, 33– 35, 38, 110
miR-192/ miR-215	Wt	Yes	*	↑/↓Proliferation, ↑/↓Chemosensitivity, ↑Cell Cycle Arrest	25, 29, 42, 44
miR-194	Wt	Yes	*	↓Proliferation, ↓Migration/ Invasion, ↑Angiogenesis	46, 47
miR-502	Wt	No	Tumor Suppressor	↓Autophagy, ↑Cell Cycle Arrest	24
miR-145	Wt	Yes	Tumor Suppressor	↓Proliferation	48, 49
miR-1204	Wt	Yes	Tumor Suppressor	↑Cell Cycle Arrest, ↑Apoptosis	50
miR-130b	Mut	No	Tumor Suppressor	↓EMT	53
miR-223	Mut	No	Tumor Suppressor	↓Chemoresistance	55
Let-7i	Mut	No	Tumor Suppressor	↓Migration/Invasion, ↓Metastasis	54

*--Role not clear, or conflicting reports in different cancer types