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. 2016 Apr 26;5:756. [Version 1] doi: 10.12688/f1000research.8363.1

Table 4. lncRNA that regulate p53 in GI Cancer.

lncRNA Regulation +/- Tumor Suppressor/
Oncogene
Function Ref.
MEG3 + Tumor Suppressor ↓Proliferation 100
H19 - Oncogene ↑Proliferation,
↓Apoptosis
101
MALAT-1 - Oncogene ↑Cell Cycle
Progression,
↑Migration/Invasion
102104
LincRNA-ROR - * ↓Apoptosis,
↓Cell Cycle Arrest
98, 105, 106

*--Role not clear, or conflicting reports in different cancer types