Figure 6.

Membrane unbinding influences polarization strength. As a measure of polarization strength, we compare the difference in concentrations of active Rac between the front and the back of the cell as a function of koff for different values of the Rac activation rate IR1 and two lengths, (a) L = 20μm and (b) L = 40μm, in all cases 200 seconds after an initial stimulus of active Rac is applied at the front of the cell. In (a), only the cell with IR1 = 0.0005 shown in red is polarized, and all three other values lead to completely unpolarized states.