Table 5. Peptides significantly changed greater than 2-fold during late-log growth phase.
Full list of detected peptides can be found in supplementary Table S5. Stress proteins induced > 3 fold are in red.
| RefSeq Locus Tag | Functional annotation | Fold Change | pValue | Predicted Fitness |
|---|---|---|---|---|
| DR_0651 | Arginase (EC 3.5.3.1) | 99.0 | 2.79E-03 | 1 |
| DR_0907 | Cold shock protein CspA | 99.0 | 6.68E-05 | 0.775 |
| DR_2394 | N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) | 43.5 | 1.21E-03 | 0.922 |
| DR_1598 | protease, putative | 12.3 | 3.76E-05 | 0.848 |
| DR_1370 | FIG00579514: hypothetical protein | 11.5 | 1.88E-03 | 1 |
| DR_0009 | Vancomycin B-type resistance protein VanW | 10.0 | 5.56E-03 | 1 |
| DR_0094 | FIG00900003: hypothetical protein | 9.3 | 6.67E-04 | 1 |
| DR_1063 | Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) | 8.8 | 1.49E-04 | 0.848 |
| DR_1891 | tetratricopeptide repeat family protein | 7.3 | 1.93E-04 | 1 |
| DR_1447 | hypothetical protein | 6.9 | 4.41E-05 | 1 |
| DR_0612 | Arginine utilization protein RocB | 5.2 | 3.07E-04 | 1 |
| DR_0606 | Heat shock protein 60 family co-chaperone GroES | 5.0 | 5.71E-04 | 0.182 |
| DR_B0125 | iron ABC transporter, periplasmic substrate-binding protein | 4.7 | 6.12E-03 | |
| DR_A0018 | 5′-nucleotidase (EC 3.1.3.5) | 4.5 | 6.21E-04 | 1 |
| DR_0121 | FIG00578909: hypothetical protein | 4.4 | 4.99E-03 | 1 |
| DR_0640 | S-adenosylmethionine synthetase (EC 2.5.1.6) | 4.0 | 1.60E-03 | 0.043 |
| DR_1624 | Cold-shock DEAD-box protein A | 3.9 | 2.53E-02 | 0.922 |
| DR_1376 | Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) | 3.3 | 3.84E-03 | 0.706 |
| DR_1335 | Isoleucyl-tRNA synthetase (EC 6.1.1.5) | 3.1 | 4.16E-03 | 0.134 |
| DR_A0184 | Pyridoxal kinase (EC 2.7.1.35) | 3.0 | 3.86E-03 | 0.922 |
| DR_0937 | tetratricopeptide repeat family protein | 3.0 | 3.29E-03 | 1 |
| DR_0960 | hypothetical protein | 2.9 | 4.00E-03 | 1 |
| DR_1915 | hypothetical protein | 2.9 | 1.36E-02 | 0.922 |
| DR_A0333 | FHA domain containing protein | 2.8 | 3.59E-02 | 0.922 |
| DR_B0014 | Vitamin B12 ABC transporter, B12-binding component BtuF | 2.8 | 7.90E-04 | |
| DR_1379 | Transcriptional regulator, TetR family | 2.4 | 2.79E-03 | 1 |
| DR_A0299 | copper resistance protein, putative | 2.3 | 8.07E-03 | 0.923 |
| DR_1407 | hypothetical protein | 2.3 | 5.65E-03 | 1 |
| DR_1465 | FIG00577987: hypothetical protein | 2.3 | 5.65E-03 | 1 |
| DR_2278 | amino acid ABC transporter, periplasmic amino acid-binding protein | 2.2 | 1.81E-03 | 0.922 |
| DR_1736 | 2′,3′-cyclic-nucleotide 2′-phosphodiesterase (EC 3.1.4.16) | 2.2 | 9.63E-04 | 0.922 |
| DR_0686 | Conserved repeat domain protein | 2.1 | 8.48E-03 | 1 |
| DR_1748 | FIG00578260: hypothetical protein | 2.1 | 5.80E-03 | 1 |
| DR_1809 | Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) | 2.1 | 2.79E-02 | 0.922 |
| DR_0608 | Histone acetyltransferase HPA2 and related acetyltransferases | 2.0 | 4.27E-03 | 1 |
| DR_0302 | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) | -2.0 | 1.59E-03 | 0.338 |
| DR_0113 | oxidoreductase, short-chain dehydrogenase/reductase family | -2.0 | 1.88E-04 | 0.922 |
| DR_0456 | MotA/TolQ/ExbB proton channel family protein | -2.0 | 6.70E-03 | 0.775 |
| DR_2221 | Tellurium resistance protein TerD | -2.0 | 1.63E-03 | 0.922 |
| DR_A0005 | Threonine dehydrogenase and related Zn-dependent dehydrogenases | -2.2 | 4.46E-02 | 0.922 |
| DR_0859 | Ribonuclease E inhibitor RraA | -2.2 | 4.40E-02 | 1 |
| DR_A0237 | Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR @ 4-hydroxybenzoyl-CoA reductase, alpha subunit (EC 1.3.99.20) | -2.2 | 1.04E-03 | 0.923 |
| DR_1132 | Dihydroxy-acid dehydratase (EC 4.2.1.9) | -2.2 | 3.68E-03 | 0.922 |
| DR_1544 | Butyryl-CoA dehydrogenase (EC 1.3.99.2) | -2.2 | 8.73E-03 | 1 |
| DR_0085 | LSU ribosomal protein L27p | -2.3 | 3.70E-02 | 0.135 |
| DR_2510 | Enoyl-CoA hydratase (EC 4.2.1.17) | -2.5 | 1.00E-05 | 1 |
| DR_1778 | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | -2.6 | 6.92E-05 | 0.847 |
| DR_2346 | 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) | -2.6 | 1.55E-03 | 0.775 |
| DR_0362 | D-alanine--D-alanine ligase A (EC 6.3.2.4) | -2.7 | 3.15E-02 | 0.232 |
| DR_1074 | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase (EC 4.2.1.-) | -2.7 | 4.27E-04 | 0.284 |
| DR_0265 | Predicted transcriptional regulator of N-Acetylglucosamine utilization, GntR family | -2.8 | 5.32E-03 | 1 |
| DR_1082 | Ribosomal subunit interface protein | -2.9 | 1.25E-04 | 0.922 |
| DR_2033 | Glutamine synthetase type III, GlnN (EC 6.3.1.2) | -3.3 | 1.24E-04 | 1 |
| DR_1055 | Aspartyl-tRNA synthetase (EC 6.1.1.12) @ Aspartyl-tRNA(Asn) synthetase (EC 6.1.1.23) | -3.4 | 1.21E-04 | 1 |
| DR_1027 | amino acid ABC transporter, periplasmic amino acid-binding protein | -3.7 | 1.61E-05 | 0.922 |
| DR_1988 | Phosphate starvation-inducible protein PhoH, predicted ATPase | -4.2 | 3.02E-03 | 0.922 |
| DR_1072 | Acetyl-CoA acetyltransferase (EC 2.3.1.9) | -5.0 | 1.07E-02 | 1 |
| DR_1645 | UDP-N-acetyl-D-mannosaminuronic acid transferase | -6.0 | 3.24E-03 | 0.847 |
| DR_B0068 | extracellular nuclease, putative | -9.3 | 4.56E-04 | |
| DR_0459 | FIG00578356: hypothetical protein | -99.0 | 1.00E-05 | 1 |