Table 2. Analyses of FTLD-CDR individual items between bvFTD vs. eoAD participants.
mean ± SD | bvftd (n= 20) | eoad (n= 24) | p |
---|---|---|---|
Memory | 0.80 ± 0.25 | 0.98 ± 0.31 | 0.045 |
Orientation | 0.60 ± 0.50 | 0.65 ± 0.35 | n.s. |
Judgment & problem solving | 1.60 ± 0.66 | 0.85 ± 0.23 | <0.001 |
Community affairs | 1.45 ± 0.67 | 0.73 ± 0.42 | <0.001 |
Home & hobbies | 1.50 ± 0.58 | 0.88 ± 0.49 | <0.001 |
Personal care | 0.90 ± 0.79 | 0.13 ± 0.34 | <0.001 |
CDR sum | 6.85 ± 2.10 | 4.21 ± 1.47 | <0.001 |
Behavior, comportment, & personality | 1.90 ± 0.31 | 0.42 ± 0.60 | <0.001 |
Language | 0.33 ± 0.37 | 0.52 ± 0.52 | n.s. |
FTLD-CDR sum | 9.08 ± 2.12 | 5.13 ± 2.07 | <0.001 |
Two-group t-test was used.
Behavioral variant frontotemporal dementia (bvFTD); Clinical Dementia Rating scale 6 item sum (CDR); Early-onset Alzheimer disease (eoAD); Frontotemporal lobar degeneration Clinical Dementia Rating scale 8 item sum (FTLD-CDR); Not significant (n.s.); Standard deviation (SD).
Higher scores indicate greater impairment (individual items scored from 0–3; CDR sum 0–18, FTLD-CDR sum 0–24).