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. Author manuscript; available in PMC: 2017 Aug 27.
Published in final edited form as: Nat Prod Rep. 2016 Apr 13;33(8):963–987. doi: 10.1039/c6np00017g

Fig. 4. The typical workflow for heterologous expression of a target BGC.

Fig. 4

1) choose a suitable heterologous host, 2) clone and/or refactor a target BGC, 3) transfer the native or refactored BGC into the heterologous host, and 4) optimize metabolite production.