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. Author manuscript; available in PMC: 2017 Jul 26.
Published in final edited form as: Circulation. 2016 Jul 26;134(4):328–338. doi: 10.1161/CIRCULATIONAHA.116.022308

Figure 5. Morphometric consequences of prostacyclin receptor (Ip) and microsomal prostaglandin E synthase 1 (mPges-1) deletion on lesion development.

Figure 5

A. Quantification of cross-sectional analysis of aortic root samples from male mice fed a 3-month high-fat diet was performed by measuring total lesion area across the aortic root, as described in methods. A parametric t-test (2-tailed) revealed a significant effect of genotype on lesion progression. Data are expressed as means ± SEMs. *p< 0.05, ***p< 0.001, n=7 per genotype (21 lesions).