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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Innate Immun. 2016 Jun 1;22(6):433–443. doi: 10.1177/1753425916651985

Figure 2.

Figure 2

Distinct TLR-mediated cytokine production by adult and newborn circulating B cells. Naïve B cells were stimulated with HKLM (109 cells/mL), R848 (10 μM), CpG (1 μM), or vehicle control for 24 hours before evaluation of supernatant cytokines by multiplex assay. Neonatal B cells demonstrated impaired TLR2- and 7- but enhanced TLR9-mediated responses. N=6-8, Student’s t-tests, * p<0.05, ** p<0.01.