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. 2015 Dec 23;66(4):581–587. doi: 10.1136/gutjnl-2015-310612

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Regional plots of association results (A) 5q14.3:88 400 000–89 400 000; (B) 1q22:152 940 379–153 897 376. Association results are based on a trend test in which –log10 p values (y axis, left) were plotted against the chromosomal positions based on hg19 (x axis). All p values were based on the discovery meta-analysis stage 1 data except for three index single-nucleotide polymorphisms (SNPs) (rs7712641 in 1a; rs80142782 and rs4072037 in (B) which were based on all data (stages 1, 2A and 2B). The line graph shows recombination rate (y axis, right). The linkage disequilibrium (LD) (r²) is colour-coded (figure legend) based on estimates from the 1000 Genomes Mar 2012 release Asian (ASN) population. The plots were generated using LocusZoom online version (URLs).