Table 3.
Maternal pre-pregnancy body mass index and neonatal iron status.
| Neonatal iron status biomarkers |
||||||||
|---|---|---|---|---|---|---|---|---|
| Log SF (μg/L) | Log sTfR (nmol/L) | Log ZPP/H (μmol/mol heme) | BI (mg/kg) | |||||
|
|
||||||||
| Coeff. | P-value | Coeff. | P-value | Coeff. | P-value | Coeff. | P-value | |
| Unadjusted analysis | ||||||||
|
| ||||||||
| Maternal pre-pregnancy BMI (kg m−2) | −0.02 | <0.001 | 0.005 | 0.04 | −0.0002 | 0.95 | −0.09 | <0.001 |
| Adjusted analysis | ||||||||
|
| ||||||||
| Maternal pre-pregnancy BMI (kg m−2) | −0.01 | 0.008 | 0.003 | 0.17 | −0.001 | 0.62 | −0.06 | 0.006 |
| Maternal age (y) | −0.01 | 0.01 | 0.003 | 0.34 | 0.004 | 0.17 | −0.06 | 0.01 |
| Previous birth | ||||||||
| No (reference) | - | - | - | - | - | - | - | - |
| Yes | 0.07 | 0.17 | 0.01 | 0.56 | −0.02 | 0.46 | 0.21 | 0.33 |
| Iron supplementation | ||||||||
| No (reference) | - | - | - | - | - | - | - | - |
| Yes | −0.02 | 0.50 | −0.001 | 0.96 | −0.02 | 0.17 | 0.12 | 0.45 |
| Gestational weight gain§ | ||||||||
| Adequate (reference) | - | - | - | - | - | - | - | - |
| Low | −0.03 | 0.63 | −0.01 | 0.73 | −0.03 | 0.39 | −0.07 | 0.81 |
| Excessive | −0.17 | <0.001 | 0.02 | 0.22 | 0.04 | 0.06 | −0.69 | <0.001 |
| Child sex | ||||||||
| Male (reference) | - | - | - | - | - | - | - | - |
| Female | 0.09 | 0.01 | −0.04 | 0.01 | −0.04 | 0.01 | 0.47 | 0.002 |
| Birth weight (kg) | −0.00 | 0.03 | −0.00 | 0.94 | −0.00 | 0.03 | −0.00 | 0.09 |
§
Gestational weight gain and maternal pre-pregnancy BMI were not found to be collinear, and so were simultaneously included in adjusted regression analyses.
Maternal iron status in late pregnancy, maternal hsCRP concentration in late pregnancy, and cord hsCRP concentration were included as additional covariates in models.