Skip to main content
. 2016 Jul 2;6(2):119–145. doi: 10.1016/j.jceh.2016.07.001

Table 3.

Recommended HCV Treatment Regimen for Patients with Decompensated Cirrhosis.

Genotype Recommended regimen
1 & 4 • SOF + LDV + RBV (initial dose of 600 mg, increased as tolerated) × 12 weeks
• SOF + DCV + RBV (initial dose of 600 mg, increased as tolerated) × 12 weeks
Alternative regimen for RBV-intolerant patients
• SOF + DCV × 24 weeks
• SOF + LDV × 12 weeks
2 • SOF + DCV + RBV (initial dose of 600 mg, increased as tolerated) × 12 weeks
3 • SOF + DCV + RBV (initial dose of 600 mg, increased as tolerated) × 24 weeks
Alternative regimen
• SOF + RBV (initial dose of 600 mg, increased as tolerated) for up to 48 weeks

DCV, daclatasvir (60 mg); LDV, ledipasvir (90 mg); RBV, Ribavirin; SOF, sofosbuvir