Figure 1.

Flow diagram for this study. ¹, of 98 patients ineligible for surgery, there were 44 LAPC patients with insufficient imaging response to neoadjuvant therapy to consider surgery. For the remaining staged as BRPC, 23 progressed on imaging to unresectable, 15 had metastases found at time of surgery, 8 were locally unresectable at time of surgery, and 8 had performance status decline during neoadjuvant therapy making them ineligible for surgery. ², due to post-operative performance status or mortality 39 patients were not offered adjuvant therapy, 5 patients refused, and 5 patients were lost to follow-up.