Table 2. Surgery characteristics and complications for all patients.

Surgical details and outcomes	Neoadjuvant therapy (n=61)	Upfront resection (n=241)	P
Surgery type			0.275
Whipple ± pylorus sparing	54 (88.5)	194 (80.5)
Distal pancreatectomy	6 (9.8)	43 (17.8)
Total pancreatectomy	1 (1.6)	4 (1.7)
SMV or PV resection or repair	22 (36.1)	19 (7.9)	<0.001
Median estimated blood loss [range], cc	500 [50–4,000]	350 [50–2,000]	0.026
No vein resection/repair	400 [100–1,500]	300 [50–2,000]	0.247
Vein resection/repair	500 [200–4,000]	400 [50–1,500]	0.298
Median surgery time [range], h	9 [6–13]	8 [4–15]	0.002
No vein resection/repair	9 [6–13]	8 [4–15]	0.014
Vein resection/repair	10 [8–13]	12 [8–14]	0.058
Median hospitalization time [range], days	10 [6–28]	12 [4–84]	0.044
No vein resection/repair	9 [6–28]	12 [4–73]	0.069
Vein resection/repair	11 [8–27]	12.5 [6–84]	0.152
Post-operative complications	24 (39.3)	75 (31.1)	0.226
Pancreatic or biliary leak	10 (16.4)	28 (12.0)	0.423
Wound infection	10 (16.4)	26 (11.6)	0.267
Wound dehiscence or fistula	3 (4.9)	3 (1.2)	0.198
Abscess	4 (6.6)	10 (4.1)	0.493
Internal bleeding	0	9 (3.7)	0.212
Stricture	1 (1.6)	1 (0.4)	0.364
Peritonitis	1 (1.6)	4 (1.7)	1.000
DVT/PE	2 (3.3)	4 (1.7)	0.350
Atrial fibrillation	4 (6.6)	16 (6.6)	1.000
90-day post-op mortality	1 (1.6)	9 (3.7)	0.693

Whipple, pancreaticoduodenectomy; SMV, superior mesenteric vein; PV, portal vein; DVT, deep venous thrombosis; PE, pulmonary embolism.