Table 1. Baseline characteristics.
Baseline characteristics | N |
---|---|
Number of patients | 11 |
Median age, years (range) | 45 [36-65] |
Median ECOG PS (range) | 1 (0-2) |
Gender | |
Male | 10 |
Female | 1 |
Median lines of prior therapy | 2 [1-5] |
Prior high dose Imatinib | 8 |
Prior sunitinib | 5 |
Prior everolimus | 2 |
Sites of disease | |
Primary site | |
Gastric | 6 |
Small bowel | 4 |
Retroperitoneal | 1 |
Metastatic site | |
Liver | 6 |
Nodes | 6 |
Peritoneal | 5 |
Lung | 1 |
Prior surgery | |
Yes | 7 |
No | 4 |
Mutation status | |
c-kit | |
Exon 11 | 3 |
Exon 9 | 1 |
Exon 17 | 1 |
PDGFRA | |
Exon 18 | 2 |
Exon 12 | 1 |
Uninterpretable | 3 |
Unavailable | 1 |
ECOG, Eastern Cooperative Oncology Group; PS, performance status; PDGFRA, platelet derived growth factor receptor alpha.