Table 4. Effects of various variables on major adverse cardiovascular events in univariate and multivariate COX regression analyses.

Variables	Crude HR	95% CI	p value	Adjusted* HR	95% CI	p value
Age: per 1 year	1.02	1.00-1.04	0.011	1.02	0.98-1.04	0.333
Male: male vs. female	1.11	0.57-2.17	0.766
Smoking: smoker vs. non-smoker	1.03	0.53-2.00	0.928
Hypertension: hypertension vs. non-hypertension	1.96	0.69-5.56	0.204
Diabetes: diabetes vs. non-diabetes	4.29	2.01-9.18	< 0.001	2.39	1.05-5.44	0.037
Cholesterol: per 1 mg/dL	1.01	1.00-1.02	0.013	1.01	1.00-1.02	0.057
CKD: CKD vs. non-CKD	3.12	1.52-6.37	0.002	2.38	1.05-5.42	0.038
hsCRP: per 1 mg/L	1.23	1.15-1.32	< 0.001	1.17	1.07-1.27	< 0.001
SYNTAX score: per +1 score	1.03	1.01-1.06	0.008	1.03	1.00-1.06	0.041
Serum bilirubin: per 1 mg/dL	0.16	0.05-0.56	0.004	0.23	0.06-0.86	0.039

CI, confidence interval; CKD, chronic kidney disease; HR, hazard ratio; hsCRP, high-sensitivity C-reactive protein.

* Adjusted for age, gender, medical history (smoking, hypertension, diabetes, CKD), serum cholesterol levels, serum hsCRP levels, SYNTAX score, and serum bilirubin levels.