Table 1. Baseline characteristics of study patients.
Parameters (N = 79) | |
Age, yrs | 84 ± 5 |
Gender, male | 51% |
Hypertension | 66% |
Diabetes mellitus | 23% |
NYHA class (I-IV) | 2.5 ± 0.5 |
Presence of AF | 28% |
CAD | 67% |
PAD | 28% |
CKD | 27% |
COPD | 37% |
Prior MI | 14% |
Prior PCI | 19% |
Prior CABG | 20% |
Prior CVE | 14% |
Echocardiography | |
Left ventricular parameters | |
Ejection fraction (%) | 53 ± 12 |
LVEDD (cm) | 4.7 ± 0.7 |
LVESD (cm) | 3.1 ± 0.8 |
LVEDV | 106 ± 44 |
LVESV | 53 ± 35 |
IVS (cm) | 1.39 ± 0.19 |
PW (cm) | 1.29 ± 0.17 |
LV mass (gr) | 302 ± 84 |
Left atrial parameters | |
LA diameter (cm) | 4.3 ± 0.5 |
LA area | 26 ± 6 |
Doppler echocardiography | |
Mitral regurgitation degree | 1.2 ± 0.7 |
Mitral regurgitation duration % | 43 ± 19 |
Mitral tenting height(cm) | 0.47 ± 0.23 |
Mitral annulus (diastolic) (cm) | 3.1 ± 0.5 |
Mitral annulus (systolic) (cm) | 2.4 ± 0.5 |
Mitral E velocity (cm/s) | 103 ± 33 |
Mitral A velocity (cm/s) | 98 ± 36 |
DT (ms) | 224 ± 75 |
Mitral inflow E duration % | 34 ± 8 |
MAC (presence) | 61% |
MAC severity (median) | 0.85 ± 0.79 [1 (0-3)] |
AVA | 0.66 ± 0.16 |
Aortic ejection duration % | 36 ± 5 |
Maximum aortic gradient (mmHg) | 84 ± 24 |
Mean aortic gradient (mmHg) | 48 ± 15 |
Aortic regurgitation | 1.6 ± 0.8 |
sPAP (mmHg) | 41 ± 14 |
Medications | |
ACEi | 47% |
Statin | 65% |
A significant p value was accepted as < 0.05.
ACEi, Angiotensin converting enzyme inhibitor; AF, atrial fibrillation; AVA, aortic valve area; CABG, coronary artery bypass graft; CAD, coronary artery disease; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVE, cerebrovascular event; DT, deceleration time; IVS, interventricular septum; LA, left atrium; LV, left ventricle; LVEDD, left ventricular end diastolic diameter; LVEDV, left ventricular end diastolic volume; LVESD, left ventricular end systolic diameter; LVESV, left ventricular end systolic volume; MAC, mitral annulus calcification; MI, myocardial infarction; NYHA, New York Heart Association; PAD, peripheral arterial disease; PAP, pulmonary artery pressure; PCI, percutaneous coronary intervention; PW, posterior wall.