FIG 3.

Core genome genealogical analysis of a global lineage 5 meningococcal population dating from 1969 through 2008. Lineage 5 meningococci (equivalent to the hyperinvasive ST-32 clonal complex identified by MLST) have been responsible for serogroup B meningococcal disease outbreaks globally for more than 30 years. In this analysis, a total of 1,752 loci (core to the lineage) were compared, identifying the presence of three distinct sublineages which were classified into the “Asian group” (sublineage 5.1), the “North European-Norwegian group” (sublineage 5.2) which contained isolates with PorA type P1.7,16, and a “Latin American group” (sublineage 5.3) with PorA type P1.19.15. (Image republished from reference 41 with permission of the publisher.)