Figure 3.

Long-term white matter microstructural development is not improved by a single injection of erythropoietin. (a) Representative T₂W images (b₀), fractional anisotropy (FA) maps, and direction encoded colour maps (DEC) of a P125 control rat (21%) derived from diffusion tensor imaging showing the different levels used for quantitative analysis. Corpus callosum (CC) and external capsule (EC) are displayed on the DEC. Diffusivity values of radial diffusivity (D _⊥), axial diffusivity (D _//), mean diffusivity (MD), and fractional anisotropy in corpus callosum (b) and external capsule (c) determined by diffusion tensor imaging out of rats exposed to normoxia (21% oxygen (21%)) or hyperoxia (24 h, 80% oxygen (80%)) at P6 and treated with normal saline or 20,000 IU/kg Epo. n = 6 rats/group. ^∗ p < 0.05, ^∗∗ p < 0.01.